MATLAB  started as a simple “Matrix Laboratory.”

Cleve Moler was one of the founders; J. H. Wilkinson, George Forsythe, and John Todd, played important roles in the origins of MATLAB.

Here is a link to “Cleve’s Corner” with an account beginning more than 50 years ago:

http://www.mathworks.com/company/newsletters/news_notes/clevescorner/dec04.html?s_cid=wiki_matlab_3